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Cholesterol-Dependent Energy Transfer between Fluorescent Proteins—Insights into Protein Proximity of APP and BACE1 in Different Membranes in Niemann-Pick Type C Disease Cells

Förster resonance energy transfer (FRET) -based techniques have recently been applied to study the interactions between β-site APP-cleaving enzyme-GFP (BACE1-GFP) and amyloid precursor protein-mRFP (APP-mRFP) in U373 glioblastoma cells. In this context, the role of APP-BACE1 proximity in Alzheimer’s...

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Detalles Bibliográficos
Autores principales:	von Einem, Bjoern, Weber, Petra, Wagner, Michael, Malnar, Martina, Kosicek, Marko, Hecimovic, Silva, von Arnim, Christine A. F., Schneckenburger, Herbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546662/ https://www.ncbi.nlm.nih.gov/pubmed/23443094 http://dx.doi.org/10.3390/ijms131215801

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