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Bacterial Over-Expression and Purification of the 3′phosphoadenosine 5′phosphosulfate (PAPS) Reductase Domain of Human FAD Synthase: Functional Characterization and Homology Modeling

FAD synthase (FADS, EC 2.7.7.2) is a key enzyme in the metabolic pathway that converts riboflavin into the redox cofactor, FAD. Human FADS is organized in two domains: -the 3′phosphoadenosine 5′phosphosulfate (PAPS) reductase domain, similar to yeast Fad1p, at the C-terminus, and -the resembling mol...

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Detalles Bibliográficos
Autores principales:	Miccolis, Angelica, Galluccio, Michele, Giancaspero, Teresa Anna, Indiveri, Cesare, Barile, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546728/ https://www.ncbi.nlm.nih.gov/pubmed/23443125 http://dx.doi.org/10.3390/ijms131216880

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