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Intron-centric estimation of alternative splicing from RNA-seq data

Motivation: Novel technologies brought in unprecedented amounts of high-throughput sequencing data along with great challenges in their analysis and interpretation. The percent-spliced-in (PSI, [Image: see text]) metric estimates the incidence of single-exon–skipping events and can be computed direc...

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Detalles Bibliográficos
Autores principales: Pervouchine, Dmitri D., Knowles, David G., Guigó, Roderic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546801/
https://www.ncbi.nlm.nih.gov/pubmed/23172860
http://dx.doi.org/10.1093/bioinformatics/bts678

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