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The effect of lipoprotein-associated phospholipase A(2) deficiency on pulmonary allergic responses in aspergillus fumigatus sensitized mice

BACKGROUND: Lipoprotein-associated phospholipase A(2) (Lp-PLA(2))/platelet-activating factor acetylhydrolase (PAF-AH) has been implicated in the pathogenesis of cardiovascular disease. A therapeutic targeting of this enzyme was challenged by the concern that increased circulating platelet activating...

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Detalles Bibliográficos
Autores principales: Jiang, Zhilong, Fehrenbach, Melane L, Ravaioli, Giulia, Kokalari, Blerina, Redai, Imre G, Sheardown, Steven A, Wilson, Stephen, Macphee, Colin, Haczku, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546878/
https://www.ncbi.nlm.nih.gov/pubmed/23140447
http://dx.doi.org/10.1186/1465-9921-13-100