The Adipocytokine Nampt and Its Product NMN Have No Effect on Beta-Cell Survival but Potentiate Glucose Stimulated Insulin Secretion

AIMS/HYPOTHESIS: Obesity is associated with a dysregulation of beta-cell and adipocyte function. The molecular interactions between adipose tissue and beta-cells are not yet fully elucidated. We investigated, whether or not the adipocytokine Nicotinamide phosphoribosyltransferase (Nampt) and its enz...

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Detalles Bibliográficos
Autores principales: Spinnler, Robert, Gorski, Theresa, Stolz, Katharina, Schuster, Susanne, Garten, Antje, Beck-Sickinger, Annette G., Engelse, Marten A., de Koning, Eelco J. P., Körner, Antje, Kiess, Wieland, Maedler, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546920/
https://www.ncbi.nlm.nih.gov/pubmed/23342086
http://dx.doi.org/10.1371/journal.pone.0054106

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