Cargando…
Acute Inactivation of PSD-95 Destabilizes AMPA Receptors at Hippocampal Synapses
Postsynatptic density protein (PSD-95) is a 95 kDa scaffolding protein that assembles signaling complexes at synapses. Over-expression of PSD-95 in primary hippocampal neurons selectively increases synaptic localization of AMPA receptors; however, mice lacking PSD-95 display grossly normal glutamate...
Autores principales: | Yudowski, Guillermo A., Olsen, Olav, Adesnik, Hillel, Marek, Kurt W., Bredt, David S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546964/ https://www.ncbi.nlm.nih.gov/pubmed/23342049 http://dx.doi.org/10.1371/journal.pone.0053965 |
Ejemplares similares
-
Cytosolic PSD-95 interactor alters functional organization of neural circuits and AMPA receptor signaling independent of PSD-95 binding
por: Rodriguez, Ana R., et al.
Publicado: (2021) -
A critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptors
por: Bhattacharyya, Samarjit, et al.
Publicado: (2009) -
Excitation Control: Balancing PSD-95 Function at the Synapse
por: Keith, Dove, et al.
Publicado: (2008) -
PSD-95 protects synapses from β-amyloid
por: Dore, Kim, et al.
Publicado: (2021) -
Regulated RalBP1 Binding to RalA and PSD-95 Controls AMPA Receptor Endocytosis and LTD
por: Han, Kihoon, et al.
Publicado: (2009)