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Activation of p53 by Chemotherapeutic Agents Enhances Reovirus Oncolysis
Mammalian reovirus is a benign virus that possesses the natural ability to preferentially infect and kill cancer cells (reovirus oncolysis). Reovirus exploits aberrant Ras signalling in many human cancers to promote its own replication and spread. In vitro and in vivo studies using reovirus either s...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546971/ https://www.ncbi.nlm.nih.gov/pubmed/23342061 http://dx.doi.org/10.1371/journal.pone.0054006 |