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The Role of Hypoxia-Inducible Factor 1α in Determining the Properties of Castrate-Resistant Prostate Cancers
BACKGROUND: Castrate-resistant prostate cancer (CRPC) is a lethal condition in patients receiving androgen deprivation therapy for prostate cancer (PC). Despite numerous studies showing the expression of HIF1α protein under normoxia in PC cell lines, the role of this normoxic HIF1α expression in che...
Autores principales: | Ranasinghe, Weranja K. B., Xiao, Lin, Kovac, Suzana, Chang, Mike, Michiels, Carine, Bolton, Damien, Shulkes, Arthur, Baldwin, Graham S., Patel, Oneel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546972/ https://www.ncbi.nlm.nih.gov/pubmed/23342109 http://dx.doi.org/10.1371/journal.pone.0054251 |
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