Genetic Association with ERAP1 in Psoriasis Is Confined to Disease Onset after Puberty and Not Dependent on HLA-C*06

HLA-C remains the strongest susceptibility candidate gene in psoriasis. Evidence for interaction between HLA-C and endoplasmic reticulum aminopeptidase 1 (ERAP1) confined to individuals carrying the HLA-C risk allele was recently reported. Psoriasis displays wide variation, and genetic heterogeneity...

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Detalles Bibliográficos
Autores principales: Lysell, Josefin, Padyukov, Leonid, Kockum, Ingrid, Nikamo, Pernilla, Ståhle, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547223/
https://www.ncbi.nlm.nih.gov/pubmed/22931917
http://dx.doi.org/10.1038/jid.2012.280

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