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Anti-ganglioside antibodies induced in chickens by an alum-adsorbed anti-idiotype antibody targeting NeuGcGM3
Racotumomab is a murine anti-idiotype cancer vaccine targeting NeuGcGM3 on melanoma, breast, and lung cancer. In order to characterize the immunogenicity of alum-adsorbed racotumomab in a non-clinical setting, Leghorn chickens were immunized in dose levels ranging from 25 μg to 1600 μg. Racotumomab...
Autores principales: | Guthmann, Marcelo D., Venier, Cecilia, Toledo, Darien, Segatori, Valeria I., Alonso, Daniel F., Fainboim, Leonardo, Vázquez, Ana M., Ostrowski, Hector |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547288/ https://www.ncbi.nlm.nih.gov/pubmed/23335925 http://dx.doi.org/10.3389/fimmu.2012.00422 |
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