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Local release of properdin in the cellular microenvironment: role in pattern recognition and amplification of the alternative pathway of complement
Properdin, the only positive regulatory protein of the complement system, acts as both a stabilizer of the alternative pathway (AP) convertases and as a selective pattern recognition molecule of certain microorganisms and host cells (i.e., apoptotic/necrotic cells) by serving as a platform for de no...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547370/ https://www.ncbi.nlm.nih.gov/pubmed/23335922 http://dx.doi.org/10.3389/fimmu.2012.00412 |