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Visual Data Mining of Biological Networks: One Size Does Not Fit All
High-throughput technologies produce massive amounts of data. However, individual methods yield data specific to the technique used and biological setup. The integration of such diverse data is necessary for the qualitative analysis of information relevant to hypotheses or discoveries. It is often u...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547662/ https://www.ncbi.nlm.nih.gov/pubmed/23341759 http://dx.doi.org/10.1371/journal.pcbi.1002833 |
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author | Pastrello, Chiara Otasek, David Fortney, Kristen Agapito, Giuseppe Cannataro, Mario Shirdel, Elize Jurisica, Igor |
author_facet | Pastrello, Chiara Otasek, David Fortney, Kristen Agapito, Giuseppe Cannataro, Mario Shirdel, Elize Jurisica, Igor |
author_sort | Pastrello, Chiara |
collection | PubMed |
description | High-throughput technologies produce massive amounts of data. However, individual methods yield data specific to the technique used and biological setup. The integration of such diverse data is necessary for the qualitative analysis of information relevant to hypotheses or discoveries. It is often useful to integrate these datasets using pathways and protein interaction networks to get a broader view of the experiment. The resulting network needs to be able to focus on either the large-scale picture or on the more detailed small-scale subsets, depending on the research question and goals. In this tutorial, we illustrate a workflow useful to integrate, analyze, and visualize data from different sources, and highlight important features of tools to support such analyses. |
format | Online Article Text |
id | pubmed-3547662 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-35476622013-01-22 Visual Data Mining of Biological Networks: One Size Does Not Fit All Pastrello, Chiara Otasek, David Fortney, Kristen Agapito, Giuseppe Cannataro, Mario Shirdel, Elize Jurisica, Igor PLoS Comput Biol Education High-throughput technologies produce massive amounts of data. However, individual methods yield data specific to the technique used and biological setup. The integration of such diverse data is necessary for the qualitative analysis of information relevant to hypotheses or discoveries. It is often useful to integrate these datasets using pathways and protein interaction networks to get a broader view of the experiment. The resulting network needs to be able to focus on either the large-scale picture or on the more detailed small-scale subsets, depending on the research question and goals. In this tutorial, we illustrate a workflow useful to integrate, analyze, and visualize data from different sources, and highlight important features of tools to support such analyses. Public Library of Science 2013-01-10 /pmc/articles/PMC3547662/ /pubmed/23341759 http://dx.doi.org/10.1371/journal.pcbi.1002833 Text en © 2013 Pastrello et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Education Pastrello, Chiara Otasek, David Fortney, Kristen Agapito, Giuseppe Cannataro, Mario Shirdel, Elize Jurisica, Igor Visual Data Mining of Biological Networks: One Size Does Not Fit All |
title | Visual Data Mining of Biological Networks: One Size Does Not Fit All |
title_full | Visual Data Mining of Biological Networks: One Size Does Not Fit All |
title_fullStr | Visual Data Mining of Biological Networks: One Size Does Not Fit All |
title_full_unstemmed | Visual Data Mining of Biological Networks: One Size Does Not Fit All |
title_short | Visual Data Mining of Biological Networks: One Size Does Not Fit All |
title_sort | visual data mining of biological networks: one size does not fit all |
topic | Education |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547662/ https://www.ncbi.nlm.nih.gov/pubmed/23341759 http://dx.doi.org/10.1371/journal.pcbi.1002833 |
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