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Human immunodeficiency virus type 1 Vpu and cellular TASK proteins suppress transcription of unintegrated HIV-1 DNA

BACKGROUND: Unintegrated HIV-1 DNA serves as transcriptionally active templates in HIV-infected cells. Several host factors including NF-κβ enhance HIV-1 transcription. HIV-1 induced NF-κβ activation can be suppressed by viral protein U (Vpu). Interestingly HIV-1 Vpu shares amino acid homology with...

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Detalles Bibliográficos
Autores principales:	Emeagwali, Nkiruka, Hildreth, James EK
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547713/ https://www.ncbi.nlm.nih.gov/pubmed/23164059 http://dx.doi.org/10.1186/1743-422X-9-277

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