Cargando…

Human immunodeficiency virus type 1 Vpu and cellular TASK proteins suppress transcription of unintegrated HIV-1 DNA

BACKGROUND: Unintegrated HIV-1 DNA serves as transcriptionally active templates in HIV-infected cells. Several host factors including NF-κβ enhance HIV-1 transcription. HIV-1 induced NF-κβ activation can be suppressed by viral protein U (Vpu). Interestingly HIV-1 Vpu shares amino acid homology with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Emeagwali, Nkiruka, Hildreth, James EK
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547713/ https://www.ncbi.nlm.nih.gov/pubmed/23164059 http://dx.doi.org/10.1186/1743-422X-9-277

Ejemplares similares

The role of unintegrated DNA in HIV infection
por: Sloan, Richard D, et al.
Publicado: (2011)

The second chance story of HIV-1 DNA: Unintegrated? Not a problem!
por: Wu, Yuntao
Publicado: (2008)

Quantification of Unintegrated HIV-1 DNA at the Single Cell Level In Vivo
por: Suspène, Rodolphe, et al.
Publicado: (2012)

Distribution and fate of HIV-1 unintegrated DNA species: a comprehensive update
por: Hamid, Faysal Bin, et al.
Publicado: (2017)

Infection of Female Primary Lower Genital Tract Epithelial Cells after Natural Pseudotyping of HIV-1: Possible Implications for Sexual Transmission of HIV-1
por: Tang, Yuyang, et al.
Publicado: (2014)

Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persistent human immunodeficiency virus type 1 infection of CEM cells
Publicado: (1990)

The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
por: Dupont, Liane, et al.
Publicado: (2021)

Oligomerization of the human immunodeficiency virus type 1 (HIV-1) Vpu protein – a genetic, biochemical and biophysical analysis
por: Hussain, Amjad, et al.
Publicado: (2007)

DNA ultra-sensitive quantification, a technology for studying HIV unintegrated linear DNA
por: Roux, Hélène Marie, et al.
Publicado: (2023)

Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration
por: Thierry, Sylvain, et al.
Publicado: (2015)

Vpu Protein: The Viroporin Encoded by HIV-1
por: González, María Eugenia
Publicado: (2015)

Two lymphoid cell lines potently silence unintegrated HIV-1 DNAs
por: Geis, Franziska K., et al.
Publicado: (2022)

The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu function
por: Kluge, Silvia F, et al.
Publicado: (2013)

NP220 mediates silencing of unintegrated retroviral DNA
por: Zhu, Yiping, et al.
Publicado: (2018)

The HIV-1 Vpu Viroporin Inhibitor BIT225 Does Not Affect Vpu-Mediated Tetherin Antagonism
por: Kuhl, Björn D., et al.
Publicado: (2011)

Unintegrated parton density functions
por: Collins, J, et al.
Publicado: (2005)

Silencing of Unintegrated Retroviral DNAs
por: Goff, Stephen P.
Publicado: (2021)

Measurements of total and integrated HIV DNA demonstrate sporadic blips of unintegrated HIV DNA in HIV-positive patients on HAART
por: Mexas, A, et al.
Publicado: (2010)

CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection
por: Geis, Franziska K., et al.
Publicado: (2022)

Opposite transcriptional regulation of integrated vs unintegrated HIV genomes by the NF-κB pathway
por: Thierry, Sylvain, et al.
Publicado: (2016)

Assembling the Transmembrane Domain of Vpu from HIV-1
por: Fischer, Wolfgang B., et al.
Publicado: (2012)

A comparative analysis of unintegrated HIV-1 DNA measurement as a potential biomarker of the cellular reservoir in the blood of patients controlling and non-controlling viral replication
por: Orlandi, Chiara, et al.
Publicado: (2020)

Expression of Nef from unintegrated HIV-1 DNA downregulates cell surface CXCR4 and CCR5 on T-lymphocytes
por: Sloan, Richard D, et al.
Publicado: (2010)

Protein expression from unintegrated HIV-1 DNA introduces bias in primary in vitro post-integration latency models
por: Bonczkowski, Pawel, et al.
Publicado: (2016)

POLE3 is a repressor of unintegrated HIV-1 DNA required for efficient virus integration and escape from innate immune sensing
por: Thenin-Houssier, Suzie, et al.
Publicado: (2023)

Analysis of the human immunodeficiency virus type 1 M group Vpu domains involved in antagonizing tetherin
por: Petit, Sarah J., et al.
Publicado: (2011)

Endpoint singularities in unintegrated parton distributions
por: Hautmann, F.
Publicado: (2007)

Effects of mutations on the subcellular distribution and localization of the HIV-1 VPU
por: Goins-Mills, Ricarda, et al.
Publicado: (2006)

Bacteria-Based Analysis of HIV-1 Vpu Channel Activity
por: Taube, Robert, et al.
Publicado: (2014)

Mechanisms underlying HIV-1 Vpu-mediated viral egress
por: Roy, Nicolas, et al.
Publicado: (2014)

The HIV-1 Accessory Protein Vpu Downregulates Peroxisome Biogenesis
por: Xu, Zaikun, et al.
Publicado: (2020)

The Human Immunodeficiency Virus Type 1 Accessory Protein Vpu Induces Apoptosis by Suppressing the Nuclear Factor κB–dependent Expression of Antiapoptotic Factors
por: Akari, Hirofumi, et al.
Publicado: (2001)

HIV-1 latency and virus production from unintegrated genomes following direct infection of resting CD4 T cells
por: Chan, Chi N., et al.
Publicado: (2016)

The Human Immunodeficiency Virus Type 1 (HIV-1) Vpu Protein Interferes with an Early Step in the Biosynthesis of Major Histocompatibility Complex (MHC) Class I Molecules
por: Kerkau, Thomas, et al.
Publicado: (1997)

Universality of Unintegrated Gluon Distributions at small x
por: Dominguez, Fabio, et al.
Publicado: (2011)

Modulation of HIV-1-host interaction: role of the Vpu accessory protein
por: Dubé, Mathieu, et al.
Publicado: (2010)

HIV-1 Vpu Interference with Innate Cell-mediated Immune Mechanisms
por: Sandberg, Johan K, et al.
Publicado: (2012)

Mechanistic study of BST-2 down-modulation by HIV-1 Vpu
por: Zhang, Jianyong, et al.
Publicado: (2009)

Functional conservation and coherence of HIV-1 subtype A Vpu alleles
por: Romani, Bizhan, et al.
Publicado: (2017)

Functional conservation and coherence of HIV-1 subtype A Vpu alleles
por: Romani, Bizhan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_bal05ud9brffdqd4ccsv2odnua