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Susceptibility of juvenile and adult blood–brain barrier to endothelin-1: regulation of P-glycoprotein and breast cancer resistance protein expression and transport activity

BACKGROUND: P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) play a critical role in keeping neurotoxic substances from entering the brain. We and others have previously reported an impact of inflammation on the regulation of adult blood–brain barrier (BBB) efflux transporters. Howe...

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Detalles Bibliográficos
Autores principales:	Harati, Rania, Villégier, Anne-Sophie, Banks, William A, Mabondzo, Aloise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547749/ https://www.ncbi.nlm.nih.gov/pubmed/23253775 http://dx.doi.org/10.1186/1742-2094-9-273

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