The efficacy and safety of a nicotine conjugate vaccine (NicVAX(®)) or placebo co-administered with varenicline (Champix(®)) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial

BACKGROUND: A potential new treatment in smoking cessation and relapse prevention is nicotine vaccination which is based on active immunization against the nicotine molecule. This immunization will elicit the immune system to produce nicotine-specific antibodies that sequester nicotine in the blood...

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Detalles Bibliográficos
Autores principales: Hoogsteder, Philippe HJ, Kotz, Daniel, van Spiegel, Paul I, Viechtbauer, Wolfgang, Brauer, Ruth, Kessler, Paul D, Kalnik, Matthew W, Fahim, Raafat EF, van Schayck, Onno CP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547752/
https://www.ncbi.nlm.nih.gov/pubmed/23216646
http://dx.doi.org/10.1186/1471-2458-12-1052

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