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Influenza A virus nucleoprotein derived from Escherichia coli or recombinant vaccinia (Tiantan) virus elicits robust cross-protection in mice

BACKGROUND: Immunity to conserved viral antigens is an attractive approach to develop a universal vaccine against epidemic and pandemic influenza. A nucleoprotein (NP)-based vaccine has been explored and preliminary studies have shown promise. However, no study has explored the immunity and cross-pr...

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Detalles Bibliográficos
Autores principales: Huang, Baoying, Wang, Wenling, Li, Renqing, Wang, Xiuping, Jiang, Tao, Qi, Xiangrong, Gao, Yingying, Tan, Wenjie, Ruan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547759/
https://www.ncbi.nlm.nih.gov/pubmed/23272943
http://dx.doi.org/10.1186/1743-422X-9-322