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Anti-thymocyte globulin (ATG) differentially depletes naïve and memory T cells and permits memory-type regulatory T cells in nonobese diabetic mice
BACKGROUND: ATG has been employed to deplete T cells in several immune-mediated conditions. However, whether ATG administration affects naïve and memory T cell differently is largely unknown. THE CONTEXT AND PURPOSE OF THE STUDY: In this study, we assessed how murine ATG therapy affected T cell subs...
Autores principales: | Xia, Chang-Qing, Chernatynskaya, Anna V, Wasserfall, Clive H, Wan, Suigui, Looney, Benjamin M, Eisenbeis, Scott, Williams, John, Clare-Salzler, Michael J, Atkinson, Mark A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547787/ https://www.ncbi.nlm.nih.gov/pubmed/23237483 http://dx.doi.org/10.1186/1471-2172-13-70 |
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