Integrative Genomics in Combination with RNA Interference Identifies Prognostic and Functionally Relevant Gene Targets for Oral Squamous Cell Carcinoma

In oral squamous cell carcinoma (OSCC), metastasis to lymph nodes is associated with a 50% reduction in 5-year survival. To identify a metastatic gene set based on DNA copy number abnormalities (CNAs) of differentially expressed genes, we compared DNA and RNA of OSCC cells laser-microdissected from...

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Detalles Bibliográficos
Autores principales: Xu, Chang, Wang, Pei, Liu, Yan, Zhang, Yuzheng, Fan, Wenhong, Upton, Melissa P., Lohavanichbutr, Pawadee, Houck, John R., Doody, David R., Futran, Neal D., Zhao, Lue Ping, Schwartz, Stephen M., Chen, Chu, Méndez, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547824/
https://www.ncbi.nlm.nih.gov/pubmed/23341773
http://dx.doi.org/10.1371/journal.pgen.1003169

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