Cargando…

Oroxylin A Inhibits Hemolysis via Hindering the Self-Assembly of α-Hemolysin Heptameric Transmembrane Pore

Alpha-hemolysin (α-HL) is a self-assembling, channel-forming toxin produced by most Staphylococcus aureus strains as a 33.2-kDa soluble monomer. Upon binding to a susceptible cell membrane, the monomer self-assembles to form a 232.4-kDa heptamer that ultimately causes host cell lysis and death. Cons...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dong, Jing, Qiu, Jiazhang, Zhang, Yu, Lu, Chongjian, Dai, Xiaohan, Wang, Jianfeng, Li, Hongen, Wang, Xin, Tan, Wei, Luo, Mingjing, Niu, Xiaodi, Deng, Xuming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547825/ https://www.ncbi.nlm.nih.gov/pubmed/23349625 http://dx.doi.org/10.1371/journal.pcbi.1002869

Ejemplares similares

Curcumin protects mice from Staphylococcus aureus pneumonia by interfering with the self-assembly process of α-hemolysin
por: Wang, Jianfeng, et al.
Publicado: (2016)

Molecular Modeling Reveals the Novel Inhibition Mechanism and Binding Mode of Three Natural Compounds to Staphylococcal α-Hemolysin
por: Qiu, Jiazhang, et al.
Publicado: (2013)

Capsaicin Protects Mice from Community-Associated Methicillin-Resistant Staphylococcus aureus Pneumonia
por: Qiu, Jiazhang, et al.
Publicado: (2012)

Chalcone Attenuates Staphylococcus aureus Virulence by Targeting Sortase A and Alpha-Hemolysin
por: Zhang, Bing, et al.
Publicado: (2017)

Structure–function mapping of a heptameric module in the nuclear pore complex
por: Fernandez-Martinez, Javier, et al.
Publicado: (2012)

COMPARATIVE KINETICS OF HEMOLYSIS INDUCED BY BACTERIAL AND OTHER HEMOLYSINS
por: Bernheimer, Alan W.
Publicado: (1947)

Application of Oleanolic Acid and Its Analogues in Combating Pathogenic Bacteria In Vitro/Vivo by a Two-Pronged Strategy of β-Lactamases and Hemolysins
por: Zhou, Yonglin, et al.
Publicado: (2020)

Two residues in Staphylococcus aureus α-hemolysin related to hemolysis and self-assembly
por: Du, Yufeng, et al.
Publicado: (2018)

Redirecting Pore Assembly of Staphylococcal α-Hemolysin by Protein Engineering
por: Koo, Sunwoo, et al.
Publicado: (2019)

Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state
por: Antoni, Claudia, et al.
Publicado: (2020)

RNase A Does Not Translocate the Alpha-Hemolysin Pore
por: Krasniqi, Besnik, et al.
Publicado: (2014)

Cryo-EM structure of human heptameric pannexin 2 channel
por: Zhang, Hang, et al.
Publicado: (2023)

Subinhibitory Concentrations of Perilla Oil Affect the Expression of Secreted Virulence Factor Genes in Staphylococcus aureus
por: Qiu, Jiazhang, et al.
Publicado: (2011)

Multiple Pleomorphic Tetramers of Thermostable Direct Hemolysin from Grimontia hollisae in Exerting Hemolysis and Membrane Binding
por: Wang, Yu-Kuo, et al.
Publicado: (2019)

Subinhibitory Concentrations of Thymol Reduce Enterotoxins A and B and α-Hemolysin Production in Staphylococcus aureus Isolates
por: Qiu, Jiazhang, et al.
Publicado: (2010)

A Natural Dietary Flavone Myricetin as an α-Hemolysin Inhibitor for Controlling Staphylococcus aureus Infection
por: Wang, Tingting, et al.
Publicado: (2020)

Structural basis for calcium-stimulating pore formation of Vibrio α-hemolysin
por: Chiu, Yu-Chuan, et al.
Publicado: (2023)

Insights into structure and activity of natural compound inhibitors of pneumolysin
por: Li, Hongen, et al.
Publicado: (2017)

Oligopeptide Targeting Sortase A as Potential Anti-infective Therapy for Staphylococcus aureus
por: Wang, Jianfeng, et al.
Publicado: (2018)

THE INHIBITION OF HEMOLYSIS, AS STUDIED BY THE TECHNIQUE USED FOR INVESTIGATING PROGRESSIVE REACTIONS, AND BY A TECHNIQUE USING RADIOACTIVE HEMOLYSINS
por: Ponder, Eric, et al.
Publicado: (1956)

ABO isohemagglutinin titration or hemolysin test: what should we do to reduce the risk of passive hemolysis?()
por: Castilho, Lilian
Publicado: (2015)

Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel
por: Ren, Yue, et al.
Publicado: (2022)

Characteristics of the Protein Complexes and Pores Formed by Bacillus cereus Hemolysin BL
por: Jessberger, Nadja, et al.
Publicado: (2020)

Cryo-EM structures of an LRRC8 chimera with native functional properties reveal heptameric assembly
por: Takahashi, Hirohide, et al.
Publicado: (2023)

Crystal structure and biochemical analysis of the heptameric Lsm1-7 complex
por: Zhou, Lijun, et al.
Publicado: (2014)

Assembly of transmembrane pores from mirror-image peptides
por: Krishnan R, Smrithi, et al.
Publicado: (2022)

β-sitosterol interacts with pneumolysin to prevent Streptococcus pneumoniae infection
por: Li, Hongen, et al.
Publicado: (2015)

Membrane-Pore Forming Characteristics of the Bordetella pertussis CyaA-Hemolysin Domain
por: Kurehong, Chattip, et al.
Publicado: (2015)

Piceatannol Alleviates Clostridium perfringens Virulence by Inhibiting Perfringolysin O
por: Wang, Guizhen, et al.
Publicado: (2022)

Computational Design of Transmembrane Pores
por: Xu, Chunfu, et al.
Publicado: (2020)

Heptameric Targeting Ligands against EGFR and HER2 with High Stability and Avidity
por: Kim, Dongwook, et al.
Publicado: (2012)

Heptameric Peptide Interferes with Amyloid-β Aggregation by Structural Reorganization of the Toxic Oligomers
por: Bhattacharyya, Rajanya, et al.
Publicado: (2020)

Pore-forming alpha-hemolysin efficiently improves the immunogenicity and protective efficacy of protein antigens
por: Zou, Jin-Tao, et al.
Publicado: (2021)

Oroxylin A inhibits colitis by inactivating NLRP3 inflammasome
por: Zhou, Wei, et al.
Publicado: (2017)

Prophylactic strategies for acute hemolysis secondary to plasma-incompatible platelet transfusions: correlation between qualitative hemolysin test and isohemagglutinin titration
por: Landim, Cinthia Silvestre, et al.
Publicado: (2015)

Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore
por: Wang, Wuyang, et al.
Publicado: (2011)

Morin Attenuates Streptococcus suis Pathogenicity in Mice by Neutralizing Suilysin Activity
por: Li, Gen, et al.
Publicado: (2017)

Distinct Stabilities of the Structurally Homologous Heptameric Co-Chaperonins GroES and gp31
por: Dyachenko, Andrey, et al.
Publicado: (2018)

Crystal structures of dimeric and heptameric mtHsp60 reveal the mechanism of chaperonin inactivation
por: Lai, Meng-Cheng, et al.
Publicado: (2023)

An Estrogen Receptor Dependent Mechanism of Oroxylin A in the Repression of Inflammatory Response
por: Wang, Hong, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_l3qgucnof6ltjuad4f1gocujm2