Cargando…
Telomerase-Null Survivor Screening Identifies Novel Telomere Recombination Regulators
Telomeres are protein–DNA structures found at the ends of linear chromosomes and are crucial for genome integrity. Telomeric DNA length is primarily maintained by the enzyme telomerase. Cells lacking telomerase will undergo senescence when telomeres become critically short. In Saccharomyces cerevisi...
Autores principales: | Hu, Yan, Tang, Hong-Bo, Liu, Ning-Ning, Tong, Xia-Jing, Dang, Wei, Duan, Yi-Min, Fu, Xiao-Hong, Zhang, Yang, Peng, Jing, Meng, Fei-Long, Zhou, Jin-Qiu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547846/ https://www.ncbi.nlm.nih.gov/pubmed/23390378 http://dx.doi.org/10.1371/journal.pgen.1003208 |
Ejemplares similares
-
Telomere Recombination Preferentially Occurs at Short Telomeres in Telomerase-Null Type II Survivors
por: Fu, Xiao-Hong, et al.
Publicado: (2014) -
Telomere Length Dynamics and Chromosomal Instability in Cells Derived from Telomerase Null Mice
por: Hande, M. Prakash, et al.
Publicado: (1999) -
ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase
por: McNees, Carolyn J., et al.
Publicado: (2010) -
Tethering telomerase to telomeres increases genome instability and promotes chronological aging in yeast
por: Liu, Jun, et al.
Publicado: (2016) -
Telomeres and telomerase in oncogenesis
por: Trybek, Tomasz, et al.
Publicado: (2020)