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A Newly Uncovered Group of Distantly Related Lysine Methyltransferases Preferentially Interact with Molecular Chaperones to Regulate Their Activity

Methylation is a post-translational modification that can affect numerous features of proteins, notably cellular localization, turnover, activity, and molecular interactions. Recent genome-wide analyses have considerably extended the list of human genes encoding putative methyltransferases. Studies...

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Detalles Bibliográficos
Autores principales: Cloutier, Philippe, Lavallée-Adam, Mathieu, Faubert, Denis, Blanchette, Mathieu, Coulombe, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547847/
https://www.ncbi.nlm.nih.gov/pubmed/23349634
http://dx.doi.org/10.1371/journal.pgen.1003210