Coordinated Degradation of Replisome Components Ensures Genome Stability upon Replication Stress in the Absence of the Replication Fork Protection Complex

The stabilization of the replisome complex is essential in order to achieve highly processive DNA replication and preserve genomic integrity. Conversely, it would also be advantageous for the cell to abrogate replisome functions to prevent inappropriate replication when fork progression is adversely...

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Detalles Bibliográficos
Autores principales: Roseaulin, Laura C., Noguchi, Chiaki, Martinez, Esteban, Ziegler, Melissa A., Toda, Takashi, Noguchi, Eishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547854/
https://www.ncbi.nlm.nih.gov/pubmed/23349636
http://dx.doi.org/10.1371/journal.pgen.1003213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547854/
https://www.ncbi.nlm.nih.gov/pubmed/23349636
http://dx.doi.org/10.1371/journal.pgen.1003213

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