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MicroRNA-22 (miR-22) Overexpression Is Neuroprotective via General Anti-Apoptotic Effects and May also Target Specific Huntington’s Disease-Related Mechanisms

BACKGROUND: Whereas many causes and mechanisms of neurodegenerative diseases have been identified, very few therapeutic strategies have emerged in parallel. One possible explanation is that successful treatment strategy may require simultaneous targeting of more than one molecule of pathway. A new t...

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Detalles Bibliográficos
Autores principales: Jovicic, Ana, Zaldivar Jolissaint, Julien Francisco, Moser, Roger, Silva Santos, Mariana de Fatima, Luthi-Carter, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547907/
https://www.ncbi.nlm.nih.gov/pubmed/23349832
http://dx.doi.org/10.1371/journal.pone.0054222