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Generation and Characterisation of Cisplatin-Resistant Non-Small Cell Lung Cancer Cell Lines Displaying a Stem-Like Signature
INTRODUCTION: Inherent and acquired cisplatin resistance reduces the effectiveness of this agent in the management of non-small cell lung cancer (NSCLC). Understanding the molecular mechanisms underlying this process may result in the development of novel agents to enhance the sensitivity of cisplat...
Autores principales: | Barr, Martin P., Gray, Steven G., Hoffmann, Andreas C., Hilger, Ralf A., Thomale, Juergen, O’Flaherty, John D., Fennell, Dean A., Richard, Derek, O’Leary, John J., O’Byrne, Kenneth J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547914/ https://www.ncbi.nlm.nih.gov/pubmed/23349823 http://dx.doi.org/10.1371/journal.pone.0054193 |
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