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Sustained Oxidative Stress Causes Late Acute Renal Failure via Duplex Regulation on p38 MAPK and Akt Phosphorylation in Severely Burned Rats
BACKGROUND: Clinical evidence indicates that late acute renal failure (ARF) predicts high mortality in severely burned patients but the pathophysiology of late ARF remains undefined. This study was designed to test the hypothesis that sustained reactive oxygen species (ROS) induced late ARF in a sev...
Autores principales: | Feng, Yafei, Liu, Yi, Wang, Lin, Cai, Xiaoqing, Wang, Dexin, Wu, Kaimin, Chen, Hongli, Li, Jia, Lei, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547934/ https://www.ncbi.nlm.nih.gov/pubmed/23349934 http://dx.doi.org/10.1371/journal.pone.0054593 |
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