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Prkcz null mice show normal learning and memory

Protein kinase M ζ (PKMζ) is a constitutively active form of atypical PKC that is exclusively expressed in the brain and implicated in the maintenance of long-term memory(1–9). Most studies that support a role for PKMζ in memory maintenance have used pharmacological PKMζ inhibitors such as the myris...

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Detalles Bibliográficos
Autores principales: Lee, Anna M., Kanter, Benjamin R., Wang, Dan, Lim, Jana P., Zou, Mimi E., Qiu, Chichen, McMahon, Tom, Dadgar, Jahan, Fischbach-Weiss, Sarah C., Messing, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548047/
https://www.ncbi.nlm.nih.gov/pubmed/23283171
http://dx.doi.org/10.1038/nature11803