Data fusion in metabolomic cancer diagnostics

We have recently shown that fluorescence spectroscopy of plasma samples has promising abilities regarding early detection of colorectal cancer. In the present paper, these results were further developed by combining fluorescence with the biomarkers, CEA and TIMP-1 and traditional metabolomic measure...

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Detalles Bibliográficos
Autores principales: Bro, Rasmus, Nielsen, Hans Jørgen, Savorani, Francesco, Kjeldahl, Karin, Christensen, Ib Jarle, Brünner, Nils, Lawaetz, Anders Juul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548087/
https://www.ncbi.nlm.nih.gov/pubmed/23335866
http://dx.doi.org/10.1007/s11306-012-0446-0
Descripción
Sumario:We have recently shown that fluorescence spectroscopy of plasma samples has promising abilities regarding early detection of colorectal cancer. In the present paper, these results were further developed by combining fluorescence with the biomarkers, CEA and TIMP-1 and traditional metabolomic measurements in the form of (1)H NMR spectroscopy. The results indicate that using an extensive profile established by combining such measurements together with the biomarkers is better than using single markers.

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