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Molecular Mechanism of Acrylamide Neurotoxicity: Lessons Learned from Organic Chemistry
Background: Acrylamide (ACR) produces cumulative neurotoxicity in exposed humans and laboratory animals through a direct inhibitory effect on presynaptic function. Objectives: In this review, we delineate how knowledge of chemistry provided an unprecedented understanding of the ACR neurotoxic mechan...
Autores principales: | LoPachin, Richard M., Gavin, Terrence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548275/ https://www.ncbi.nlm.nih.gov/pubmed/23060388 http://dx.doi.org/10.1289/ehp.1205432 |
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