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Intracellular delivery of doxorubicin encapsulated in novel pH-responsive chitosan/heparin nanocapsules
A novel polyelectrolyte nanocapsule system composed of biopolymers, chitosan and heparin has been fabricated by the layer-by-layer technique on silica nanoparticles followed by dissolution of the silica core. The nanocapsules were of the size range 200 ± 20 nm and loaded with the positively charged...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548417/ https://www.ncbi.nlm.nih.gov/pubmed/23345974 http://dx.doi.org/10.2147/IJN.S37737 |