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Deficiency of CCAAT/enhancer binding protein family DNA binding prevents malignant conversion of adenoma to carcinoma in NNK-induced lung carcinogenesis in the mouse
BACKGROUND: The CCAAT/enhancer binding proteins (C/EBPs) play important roles in carcinogenesis of many tumors including the lung. Since multiple C/EBPs are expressed in lung, the combinatorial expression of these C/EBPs on lung carcinogenesis is not known. METHODS: A transgenic mouse line expressin...
Autores principales: | Kimura, Shioko, Paiz, Jorge, Yoneda, Mitsuhiro, Kido, Taketomo, Vinson, Charles, Ward, Jerrold M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548712/ https://www.ncbi.nlm.nih.gov/pubmed/23234329 http://dx.doi.org/10.1186/1476-4598-11-90 |
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