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A model of binding on DNA microarrays: understanding the combined effect of probe synthesis failure, cross-hybridization, DNA fragmentation and other experimental details of affymetrix arrays

BACKGROUND: DNA microarrays are used both for research and for diagnostics. In research, Affymetrix arrays are commonly used for genome wide association studies, resequencing, and for gene expression analysis. These arrays provide large amounts of data. This data is analyzed using statistical method...

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Detalles Bibliográficos
Autores principales:	Jakubek, Yasminka A, Cutler, David J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548757/ https://www.ncbi.nlm.nih.gov/pubmed/23270536 http://dx.doi.org/10.1186/1471-2164-13-737

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