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Absence of Platelet Phenotype in Mice Lacking the Motor Protein Myosin Va

BACKGROUND: The motor protein myosin Va plays an important role in the trafficking of intracellular vesicles. Mutation of the Myo5a gene causes Griscelli syndrome type 1 in humans and the dilute phenotype in mice, which are both characterised by pigment dilution and neurological defects as a result...

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Detalles Bibliográficos
Autores principales: Harper, Matthew T., van den Bosch, Marion T. J., Hers, Ingeborg, Poole, Alastair W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548825/
https://www.ncbi.nlm.nih.gov/pubmed/23349704
http://dx.doi.org/10.1371/journal.pone.0053239