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Variants in the 15q24/25 Locus Associate with Lung Function Decline in Active Smokers

Genetic variation in nicotinic acetylcholine receptor subunit genes (nAChRs) is associated with lung function level and chronic obstructive pulmonary disease (COPD). It is unknown whether these variants also predispose to an accelerated lung function decline. We investigated the association of nAChR...

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Detalles Bibliográficos
Autores principales: Mohamed Hoesein, Firdaus A. A., Wauters, Els, Janssens, Wim, Groen, Harry J. M., Smolonska, Joanna, Wijmenga, Cisca, Postma, Dirkje S., Boezen, H. Marike, De Jong, Pim A., Decramer, Marc, Lammers, Jan-Willem J., Lambrechts, Diether, Zanen, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548843/
https://www.ncbi.nlm.nih.gov/pubmed/23349703
http://dx.doi.org/10.1371/journal.pone.0053219