Cargando…

Configuration and Performance of a Mobile (129)Xe Polarizer

A stand-alone, self-contained and transportable system for the polarization of (129)Xe by spin exchange optical pumping with Rb is described. This mobile polarizer may be operated in batch or continuous flow modes with medium amounts of hyperpolarized (129)Xe for spectroscopic or small animal applic...

Descripción completa

Detalles Bibliográficos
Autores principales: Korchak, Sergey E., Kilian, Wolfgang, Mitschang, Lorenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549238/
https://www.ncbi.nlm.nih.gov/pubmed/23349565
http://dx.doi.org/10.1007/s00723-012-0425-7
_version_ 1782256394749083648
author Korchak, Sergey E.
Kilian, Wolfgang
Mitschang, Lorenz
author_facet Korchak, Sergey E.
Kilian, Wolfgang
Mitschang, Lorenz
author_sort Korchak, Sergey E.
collection PubMed
description A stand-alone, self-contained and transportable system for the polarization of (129)Xe by spin exchange optical pumping with Rb is described. This mobile polarizer may be operated in batch or continuous flow modes with medium amounts of hyperpolarized (129)Xe for spectroscopic or small animal applications. A key element is an online nuclear magnetic resonance module which facilitates continuous monitoring of polarization generation in the pumping cell as well as the calculation of the absolute (129)Xe polarization. The performance of the polarizer with respect to the crucial parameters temperature, xenon and nitrogen partial pressures, and the total gas flow is discussed. In batch mode the highest (129)Xe polarization of P(Xe) = 40 % was achieved using 0.1 mbar xenon partial pressure. For a xenon flow of 6.5 and 26 mln/min, P (Xe) = 25 % and P (Xe) = 13 % were reached, respectively. The mobile polarizer may be a practical and efficient means to make the applicability of hyperpolarized (129)Xe more widespread.
format Online
Article
Text
id pubmed-3549238
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Springer Vienna
record_format MEDLINE/PubMed
spelling pubmed-35492382013-01-22 Configuration and Performance of a Mobile (129)Xe Polarizer Korchak, Sergey E. Kilian, Wolfgang Mitschang, Lorenz Appl Magn Reson Article A stand-alone, self-contained and transportable system for the polarization of (129)Xe by spin exchange optical pumping with Rb is described. This mobile polarizer may be operated in batch or continuous flow modes with medium amounts of hyperpolarized (129)Xe for spectroscopic or small animal applications. A key element is an online nuclear magnetic resonance module which facilitates continuous monitoring of polarization generation in the pumping cell as well as the calculation of the absolute (129)Xe polarization. The performance of the polarizer with respect to the crucial parameters temperature, xenon and nitrogen partial pressures, and the total gas flow is discussed. In batch mode the highest (129)Xe polarization of P(Xe) = 40 % was achieved using 0.1 mbar xenon partial pressure. For a xenon flow of 6.5 and 26 mln/min, P (Xe) = 25 % and P (Xe) = 13 % were reached, respectively. The mobile polarizer may be a practical and efficient means to make the applicability of hyperpolarized (129)Xe more widespread. Springer Vienna 2012-11-10 2013 /pmc/articles/PMC3549238/ /pubmed/23349565 http://dx.doi.org/10.1007/s00723-012-0425-7 Text en © The Author(s) 2012 https://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Article
Korchak, Sergey E.
Kilian, Wolfgang
Mitschang, Lorenz
Configuration and Performance of a Mobile (129)Xe Polarizer
title Configuration and Performance of a Mobile (129)Xe Polarizer
title_full Configuration and Performance of a Mobile (129)Xe Polarizer
title_fullStr Configuration and Performance of a Mobile (129)Xe Polarizer
title_full_unstemmed Configuration and Performance of a Mobile (129)Xe Polarizer
title_short Configuration and Performance of a Mobile (129)Xe Polarizer
title_sort configuration and performance of a mobile (129)xe polarizer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549238/
https://www.ncbi.nlm.nih.gov/pubmed/23349565
http://dx.doi.org/10.1007/s00723-012-0425-7
work_keys_str_mv AT korchaksergeye configurationandperformanceofamobile129xepolarizer
AT kilianwolfgang configurationandperformanceofamobile129xepolarizer
AT mitschanglorenz configurationandperformanceofamobile129xepolarizer