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Effect of repetitive lysine–tryptophan motifs on the bactericidal activity of antimicrobial peptides

Previous studies identified lysine- and tryptophan-rich sequences within various cationic antimicrobial peptides. In the present study, we synthesized a series of peptides composed of lysine (K)-tryptophan (W) repeats (KW)(n) (where n equals 2, 3, 4 or 5) with amidation of the C-terminal to increase...

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Detalles Bibliográficos
Autores principales: Gopal, Ramamourthy, Seo, Chang Ho, Song, Peter I., Park, Yoonkyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549253/
https://www.ncbi.nlm.nih.gov/pubmed/22914980
http://dx.doi.org/10.1007/s00726-012-1388-6

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