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Ablation of PGC1 beta prevents mTOR dependent endoplasmic reticulum stress response

Mitochondria dysfunction contributes to the pathophysiology of obesity, diabetes, neurodegeneration and ageing. The peroxisome proliferator-activated receptor-gamma coactivator-1β (PGC-1β) coordinates mitochondrial biogenesis and function as well as fatty acid metabolism. It has been suggested that...

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Detalles Bibliográficos
Autores principales:	Camacho, Alberto, Rodriguez-Cuenca, Sergio, Blount, Margaret, Prieur, Xavier, Barbarroja, Nuria, Fuller, Maria, Hardingham, Giles E., Vidal-Puig, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549498/ https://www.ncbi.nlm.nih.gov/pubmed/22771762 http://dx.doi.org/10.1016/j.expneurol.2012.06.031

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