APG: an Active Protein-Gene Network Model to Quantify Regulatory Signals in Complex Biological Systems

Synergistic interactions among transcription factors (TFs) and their cofactors collectively determine gene expression in complex biological systems. In this work, we develop a novel graphical model, called Active Protein-Gene (APG) network model, to quantify regulatory signals of transcription in co...

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Detalles Bibliográficos
Autores principales: Wang, Jiguang, Sun, Yidan, Zheng, Si, Zhang, Xiang-Sun, Zhou, Huarong, Chen, Luonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549541/
https://www.ncbi.nlm.nih.gov/pubmed/23346354
http://dx.doi.org/10.1038/srep01097

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