A distinct subset of human NK cells expressing HLA-DR expand in response to IL-2 and can aid immune responses to BCG

Subsets of NK cells can have distinct functions. Here, we report that >25% of human peripheral blood NK cells express HLA-DR after culture with IL-2. This can be driven by an expansion of a small subset of NK cells expressing HLA-DR, in contrast to previous assumptions that HLA-DR is upregulated...

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Detalles Bibliográficos
Autores principales: Evans, J Henry, Horowitz, Amir, Mehrabi, Maryam, Wise, Emma L, Pease, James E, Riley, Eleanor M, Davis, Daniel M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Cellular Immune Response
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549558/
https://www.ncbi.nlm.nih.gov/pubmed/21491418
http://dx.doi.org/10.1002/eji.201041180

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