Viral and Developmental Cell Fusion Mechanisms: Conservation and Divergence

Membrane fusion is a fundamental requirement in numerous developmental, physiological, and pathological processes in eukaryotes. So far, only a limited number of viral and cellular fusogens, proteins that fuse membranes, have been isolated and characterized. Despite the diversity in structures and f...

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Autores principales: Sapir, Amir, Avinoam, Ori, Podbilewicz, Benjamin, Chernomordik, Leonid V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549671/
https://www.ncbi.nlm.nih.gov/pubmed/18194649
http://dx.doi.org/10.1016/j.devcel.2007.12.008
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author Sapir, Amir
Avinoam, Ori
Podbilewicz, Benjamin
Chernomordik, Leonid V.
author_facet Sapir, Amir
Avinoam, Ori
Podbilewicz, Benjamin
Chernomordik, Leonid V.
author_sort Sapir, Amir
collection PubMed
description Membrane fusion is a fundamental requirement in numerous developmental, physiological, and pathological processes in eukaryotes. So far, only a limited number of viral and cellular fusogens, proteins that fuse membranes, have been isolated and characterized. Despite the diversity in structures and functions of known fusogens, some common principles of action apply to all fusion reactions. These can serve as guidelines in the search for new fusogens, and may allow the formulation of a cross-species, unified theory to explain divergent and convergent evolutionary principles of membrane fusion.
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spelling pubmed-35496712013-01-21 Viral and Developmental Cell Fusion Mechanisms: Conservation and Divergence Sapir, Amir Avinoam, Ori Podbilewicz, Benjamin Chernomordik, Leonid V. Dev Cell Article Membrane fusion is a fundamental requirement in numerous developmental, physiological, and pathological processes in eukaryotes. So far, only a limited number of viral and cellular fusogens, proteins that fuse membranes, have been isolated and characterized. Despite the diversity in structures and functions of known fusogens, some common principles of action apply to all fusion reactions. These can serve as guidelines in the search for new fusogens, and may allow the formulation of a cross-species, unified theory to explain divergent and convergent evolutionary principles of membrane fusion. Elsevier Inc. 2008-01 2008-01-14 /pmc/articles/PMC3549671/ /pubmed/18194649 http://dx.doi.org/10.1016/j.devcel.2007.12.008 Text en Copyright © 2008 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Sapir, Amir
Avinoam, Ori
Podbilewicz, Benjamin
Chernomordik, Leonid V.
Viral and Developmental Cell Fusion Mechanisms: Conservation and Divergence
title Viral and Developmental Cell Fusion Mechanisms: Conservation and Divergence
title_full Viral and Developmental Cell Fusion Mechanisms: Conservation and Divergence
title_fullStr Viral and Developmental Cell Fusion Mechanisms: Conservation and Divergence
title_full_unstemmed Viral and Developmental Cell Fusion Mechanisms: Conservation and Divergence
title_short Viral and Developmental Cell Fusion Mechanisms: Conservation and Divergence
title_sort viral and developmental cell fusion mechanisms: conservation and divergence
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549671/
https://www.ncbi.nlm.nih.gov/pubmed/18194649
http://dx.doi.org/10.1016/j.devcel.2007.12.008
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AT chernomordikleonidv viralanddevelopmentalcellfusionmechanismsconservationanddivergence

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