Cargando…

LECT2 protects mice against bacterial sepsis by activating macrophages via the CD209a receptor

Leukocyte cell–derived chemotaxin 2 (LECT2) is a multifunctional cytokine and reduced plasma levels were found in patients with sepsis. However, precise functions and mechanisms of LECT2 remain unclear. The aim of the present study was to determine the role of LECT2 in modulating immune responses us...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Xin-Jiang, Chen, Jiong, Yu, Chao-Hui, Shi, Yu-Hong, He, Yu-Qing, Zhang, Rui-Cheng, Huang, Zuo-An, Lv, Ji-Neng, Zhang, Shun, Xu, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549712/ https://www.ncbi.nlm.nih.gov/pubmed/23254286 http://dx.doi.org/10.1084/jem.20121466

Ejemplares similares

LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells
por: Lu, Xin-Jiang, et al.
Publicado: (2016)

CD40 Signaling Is Impaired in L. major–infected Macrophages and Is Rescued by a p38MAPK Activator Establishing a Host-protective Memory T Cell Response
por: Awasthi, Amit, et al.
Publicado: (2003)

LECT2 Protects Nile Tilapia (Oreochromis niloticus) Against Streptococcus agalatiae Infection
por: Li, Qi, et al.
Publicado: (2021)

Endogenous IRBP can be dispensable for generation of natural CD4(+)CD25(+) regulatory T cells that protect from IRBP-induced retinal autoimmunity
por: Grajewski, Rafael S., et al.
Publicado: (2006)

Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis
por: de Jager, Saskia C.A., et al.
Publicado: (2011)

Cd47 (Integrin-Associated Protein) Engagement of Dendritic Cell and Macrophage Counterreceptors Is Required to Prevent the Clearance of Donor Lymphohematopoietic Cells
por: Blazar, Bruce R., et al.
Publicado: (2001)

Protection from cytomegalovirus after transplantation is correlated with immediate early 1–specific CD8 T cells
por: Bunde, Torsten, et al.
Publicado: (2005)

Hepatic FGF21 preserves thermoregulation and cardiovascular function during bacterial inflammation
por: Huen, Sarah C., et al.
Publicado: (2021)

Protection from Respiratory Virus Infections Can Be Mediated by Antigen-Specific Cd4(+) T Cells That Persist in the Lungs
por: Hogan, Robert J., et al.
Publicado: (2001)

Role of HMGB1 in apoptosis-mediated sepsis lethality
por: Qin, Shixin, et al.
Publicado: (2006)

CD8(−) DCs induce IL-12–independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS
por: Skokos, Dimitris, et al.
Publicado: (2007)

Type I interferon signaling mediates Mycobacterium tuberculosis–induced macrophage death
por: Zhang, Li, et al.
Publicado: (2020)

Toll-like receptor 9 inhibition reduces mortality in polymicrobial sepsis
por: Plitas, George, et al.
Publicado: (2008)

Cd8 Expression up to the Double-Positive CD3(Low/Intermediate) Stage of Thymic Differentiation Is Sufficient for Development of Peripheral Functional Cytotoxic T Lymphocytes
por: Zhang, X.-L., et al.
Publicado: (2001)

Restoration of CD28 Expression in CD28(−) CD8(+) Memory Effector T Cells Reconstitutes Antigen-induced IL-2 Production
por: Topp, Max S., et al.
Publicado: (2003)

CD40-deficient, Influenza-specific CD8 Memory T Cells Develop and Function Normally in a CD40-sufficient Environment
por: Lee, Byung O., et al.
Publicado: (2003)

Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis
por: Huston, Jared M., et al.
Publicado: (2006)

METABOLIC AND FUNCTIONAL STUDIES ON ACTIVATED MOUSE MACROPHAGES
por: Stubbs, Marion, et al.
Publicado: (1973)

Definition of target antigens for naturally occurring CD4(+) CD25(+) regulatory T cells
por: Nishikawa, Hiroyoshi, et al.
Publicado: (2005)

Quantitative Contribution of CD4 and CD8 to T Cell Antigen Receptor Serial Triggering
por: Viola, Antonella, et al.
Publicado: (1997)

Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation
por: Jenkinson, S. Rhiannon, et al.
Publicado: (2007)

FcγRIIb Balances Efficient Pathogen Clearance and the Cytokine-mediated Consequences of Sepsis
por: Clatworthy, Menna R., et al.
Publicado: (2004)

Increased frequencies of CD4(+)CD25(high) regulatory T cells in acute dengue infection
por: Lühn, Kerstin, et al.
Publicado: (2007)

CD4(+)CD25(+) Immunoregulatory T Cells: New Therapeutics for Graft-Versus-Host Disease
por: Cohen, José L., et al.
Publicado: (2002)

High Level Expression of Cd43 Inhibits T Cell Receptor/CD3-Mediated Apoptosis
por: He, You-Wen, et al.
Publicado: (1999)

CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding
por: Renard, Valery, et al.
Publicado: (1996)

The Modulation of CD40 Ligand Signaling by Transmembrane CD28 Splice Variant in Human T Cells
por: Mikolajczak, Sebastian A., et al.
Publicado: (2004)

NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4(+) T lymphocytes by CD4(+) CD25(+) regulatory T cells
por: Bopp, Tobias, et al.
Publicado: (2005)

CRTAM controls residency of gut CD4(+)CD8(+) T cells in the steady state and maintenance of gut CD4(+) Th17 during parasitic infection
por: Cortez, Victor S., et al.
Publicado: (2014)

Dynamic Interactions of Macrophages with T Cells during Antigen Presentation
por: Underhill, David M., et al.
Publicado: (1999)

Progressive replacement of embryo-derived cardiac macrophages with age
por: Molawi, Kaaweh, et al.
Publicado: (2014)

Imaging resident and recruited macrophage contribution to Wallerian degeneration
por: Boissonnas, Alexandre, et al.
Publicado: (2020)

The Functional Paradox of CD43 in Leukocyte Recruitment: A Study Using CD43-deficient Mice
por: Woodman, Richard C., et al.
Publicado: (1998)

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
por: Deaglio, Silvia, et al.
Publicado: (2007)

Rapid Turnover of Effector–Memory CD4(+) T Cells in Healthy Humans
por: Macallan, Derek C., et al.
Publicado: (2004)

Elongated neutrophil-derived structures are blood-borne microparticles formed by rolling neutrophils during sepsis
por: Marki, Alex, et al.
Publicado: (2020)

CD11b facilitates the development of peripheral tolerance by suppressing Th17 differentiation
por: Ehirchiou, Driss, et al.
Publicado: (2007)

Expansion and tissue infiltration of an allospecific CD4(+)CD25(+)CD45RO(+)IL-7Rα(high) cell population in solid organ transplant recipients
por: Codarri, Laura, et al.
Publicado: (2007)

Murine Macrophages Secrete Interferon γ upon Combined Stimulation with Interleukin (IL)-12 and IL-18: A Novel Pathway of Autocrine Macrophage Activation
por: Munder, Markus, et al.
Publicado: (1998)

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8(+) T cells
por: Gattinoni, Luca, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_6s80fe31qn56v4tmolbruvdh79