Revisiting the relationship between regenerative ability and aging

Contrary to the longstanding view that newts (Notophthalamus viridescens), but not axolotls (Ambystoma mexicanum), can regenerate a lens, a recent report in BMC Biology by Panagiotis Tsonis and colleagues shows axolotls indeed possess this ability during early larval stages. In contrast, they show t...

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Detalles Bibliográficos
Autores principales: Seifert, Ashley W, Voss, S Randal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549786/
https://www.ncbi.nlm.nih.gov/pubmed/23336699
http://dx.doi.org/10.1186/1741-7007-11-2
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author Seifert, Ashley W
Voss, S Randal
author_facet Seifert, Ashley W
Voss, S Randal
author_sort Seifert, Ashley W
collection PubMed
description Contrary to the longstanding view that newts (Notophthalamus viridescens), but not axolotls (Ambystoma mexicanum), can regenerate a lens, a recent report in BMC Biology by Panagiotis Tsonis and colleagues shows axolotls indeed possess this ability during early larval stages. In contrast, they show that zebrafish never posses this ability, even as embryos. This underscores the importance of comparing regenerative ability across species and reinforces the need to consider organ regeneration in the context of evolution, development, and aging. See research article: http://www.biomedcentral.com/1741-7007/10/103
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spelling pubmed-35497862013-01-23 Revisiting the relationship between regenerative ability and aging Seifert, Ashley W Voss, S Randal BMC Biol Commentary Contrary to the longstanding view that newts (Notophthalamus viridescens), but not axolotls (Ambystoma mexicanum), can regenerate a lens, a recent report in BMC Biology by Panagiotis Tsonis and colleagues shows axolotls indeed possess this ability during early larval stages. In contrast, they show that zebrafish never posses this ability, even as embryos. This underscores the importance of comparing regenerative ability across species and reinforces the need to consider organ regeneration in the context of evolution, development, and aging. See research article: http://www.biomedcentral.com/1741-7007/10/103 BioMed Central 2013-01-21 /pmc/articles/PMC3549786/ /pubmed/23336699 http://dx.doi.org/10.1186/1741-7007-11-2 Text en Copyright ©2012 Seifert and Voss; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Seifert, Ashley W
Voss, S Randal
Revisiting the relationship between regenerative ability and aging
title Revisiting the relationship between regenerative ability and aging
title_full Revisiting the relationship between regenerative ability and aging
title_fullStr Revisiting the relationship between regenerative ability and aging
title_full_unstemmed Revisiting the relationship between regenerative ability and aging
title_short Revisiting the relationship between regenerative ability and aging
title_sort revisiting the relationship between regenerative ability and aging
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549786/
https://www.ncbi.nlm.nih.gov/pubmed/23336699
http://dx.doi.org/10.1186/1741-7007-11-2
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