O6-methylguanine-DNA methyltransferase (MGMT) Promoter methylation is a rare event in soft tissue sarcoma

BACKGROUND: Gene silencing of O6-methylguanine–DNA methyltransferase (MGMT) by promoter methylation improves the outcome of glioblastoma patients after combined therapy of alkylating chemotherapeutic agents and radiation. The purpose of this study was to assess the frequency of MGMT promoter methyla...

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Detalles Bibliográficos
Autores principales: Jakob, Jens, Hille, Maren, Sauer, Christian, Ströbel, Philipp, Wenz, Frederik, Hohenberger, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549846/
https://www.ncbi.nlm.nih.gov/pubmed/23110891
http://dx.doi.org/10.1186/1748-717X-7-180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549846/
https://www.ncbi.nlm.nih.gov/pubmed/23110891
http://dx.doi.org/10.1186/1748-717X-7-180

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