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Long-Term Follow-Up Result of Hydroxyurea Chemotherapy for Recurrent Meningiomas

OBJECTIVE: Meningiomas represent 18-20% of all intracranial tumors and have a 20-50% 10-year recurrence rate, despite aggressive surgery and irradiation. Hydroxyurea, an inhibitor of ribonucleotide reductase, is known to inhibit meningioma cells by induction of apoptosis. We report the long-term fol...

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Detalles Bibliográficos
Autores principales: Kim, Min-Su, Yu, Dong-Woo, Jung, Young-Jin, Kim, Sang Woo, Chang, Chul-Hoon, Kim, Oh-Lyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Neurosurgical Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3550418/
https://www.ncbi.nlm.nih.gov/pubmed/23346322
http://dx.doi.org/10.3340/jkns.2012.52.6.517