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Jdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygosity

We performed a genetic screen in mice to identify candidate genes that are associated with leukaemogenesis in the context of Trp53 heterozygosity. To do this we generated Trp53 heterozygous mice carrying the T2/Onc transposon and SB11 transposase alleles to allow transposon-mediated insertional muta...

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Detalles Bibliográficos
Autores principales:	van der Weyden, L, Rust, A G, McIntyre, R E, Robles-Espinoza, C D, del Castillo Velasco-Herrera, M, Strogantsev, R, Ferguson-Smith, A C, McCarthy, S, Keane, T M, Arends, M J, Adams, D J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3550594/ https://www.ncbi.nlm.nih.gov/pubmed/22370638 http://dx.doi.org/10.1038/onc.2012.56

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