Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY)

OBJECTIVE: In patients with active rheumatoid arthritis (RA) despite methotrexate, to compare the efficacy of adding tocilizumab to that of switching to tocilizumab monotherapy. METHODS: Double-blind, 2-year study in which adults with active RA (DAS28 >4.4) despite methotrexate were randomly assi...

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Detalles Bibliográficos
Autores principales: Dougados, Maxime, Kissel, Karsten, Sheeran, Tom, Tak, Paul P, Conaghan, Philip G, Mola, Emilio Martín, Schett, Georg, Amital, Howard, Navarro-Sarabia, Federico, Hou, Antony, Bernasconi, Corrado, Huizinga, TWJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2013
Materias:
Clinical and Epidemiological Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551223/
https://www.ncbi.nlm.nih.gov/pubmed/22562983
http://dx.doi.org/10.1136/annrheumdis-2011-201282

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