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Heterologous viral expression systems in fosmid vectors increase the functional analysis potential of metagenomic libraries
The extraordinary potential of metagenomic functional analyses to identify activities of interest present in uncultured microorganisms has been limited by reduced gene expression in surrogate hosts. We have developed vectors and specialized E. coli strains as improved metagenomic DNA heterologous ex...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551230/ https://www.ncbi.nlm.nih.gov/pubmed/23346364 http://dx.doi.org/10.1038/srep01107 |