Cargando…
High-Throughput Multiplexed Quantitation of Protein Aggregation and Cytotoxicity in a Huntington’s Disease Model
A hallmark of Huntington’s disease is the presence of a large polyglutamine expansion in the first exon of the Huntingtin protein and the propensity of protein aggregation by the mutant proteins. Aberrant protein aggregation also occurs in other polyglutamine expansion disorders, as well as in other...
Autores principales: | Titus, Steven A, Southall, Noel, Marugan, Juan, Austin, Christopher P, Zheng, Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551243/ https://www.ncbi.nlm.nih.gov/pubmed/23346268 http://dx.doi.org/10.2174/1875397301206010079 |
Ejemplares similares
-
Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening
por: Xia, Menghang, et al.
Publicado: (2008) -
High Throughput Screening for Inhibitors of Alpha-Galactosidase
por: Motabar, Omid, et al.
Publicado: (2010) -
High Throughput Screening for Small Molecule Therapy for Gaucher Disease Using Patient Tissue as the Source of Mutant Glucocerebrosidase
por: Goldin, Ehud, et al.
Publicado: (2012) -
A Microfluidic Platform for High-Throughput Multiplexed Protein Quantitation
por: Volpetti, Francesca, et al.
Publicado: (2015) -
A High Throughput Screening Assay System for the Identification of Small Molecule Inhibitors of gsp
por: Bhattacharyya, Nisan, et al.
Publicado: (2014)