A cell-based screening system for influenza A viral RNA transcription/replication inhibitors

Although two classes of antivirals, NA inhibitors and M2 ion channel blockers, are licensed for influenza treatment, dual resistant mutants, including highly pathogenic H5N1 viruses, have appeared. Alternative treatment options are, therefore, needed. Influenza A viral RNA (vRNA) transcription/repli...

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Detalles Bibliográficos
Autores principales: Ozawa, Makoto, Shimojima, Masayuki, Goto, Hideo, Watanabe, Shinji, Hatta, Yasuko, Kiso, Maki, Furuta, Yousuke, Horimoto, Taisuke, Peters, Noel R., Hoffmann, F. Michael, Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551287/
https://www.ncbi.nlm.nih.gov/pubmed/23346363
http://dx.doi.org/10.1038/srep01106

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