Interleukin-7 receptor blockade suppresses adaptive and innate inflammatory responses in experimental colitis

BACKGROUND: Interleukin-7 (IL-7) acts primarily on T cells to promote their differentiation, survival, and homeostasis. Under disease conditions, IL-7 mediates inflammation through several mechanisms and cell types. In humans, IL-7 and its receptor (IL-7R) are increased in diseases characterized by...

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Detalles Bibliográficos
Autores principales: Willis, Cynthia R, Seamons, Audrey, Maxwell, Joe, Treuting, Piper M, Nelson, Laurel, Chen, Guang, Phelps, Susan, Smith, Carole L, Brabb, Thea, Iritani, Brian M, Maggio-Price, Lillian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551718/
https://www.ncbi.nlm.nih.gov/pubmed/23057802
http://dx.doi.org/10.1186/1476-9255-9-39

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