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A Potential Role for Plasma Uric Acid in the Endothelial Pathology of Plasmodium falciparum malaria

BACKGROUND: Inflammatory cytokinemia and systemic activation of the microvascular endothelium are central to the pathogenesis of Plasmodium falciparum malaria. Recently, ‘parasite-derived’ uric acid (UA) was shown to activate human immune cells in vitro, and plasma UA levels were associated with inf...

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Detalles Bibliográficos
Autores principales:	Mita-Mendoza, Neida K., van de Hoef, Diana L., Lopera-Mesa, Tatiana M., Doumbia, Saibou, Konate, Drissa, Doumbouya, Mory, Gu, Wenjuan, Anderson, Jennifer M., Santos-Argumedo, Leopoldo, Rodriguez, Ana, Fay, Michael P., Diakite, Mahamadou, Long, Carole A., Fairhurst, Rick M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551755/ https://www.ncbi.nlm.nih.gov/pubmed/23349902 http://dx.doi.org/10.1371/journal.pone.0054481

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